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You are taking this medicine. Glucophage tablets are standard release tablets that are taken two or three times a day either during or just after meals. If the patient is taking Glucophage tablets, the starting dose is 500 mg daily with the evening meal. If the patient is taking Glucophage tablets, the starting dose is 500 mg daily with the evening meal or as directed by your doctor. Glucophage does not increase the body's production of insulin. Metformin decreases the amount of glucose made by your liver.